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KMID : 0356820140300010005
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Korean Journal of Head & Neck Oncology
2014 Volume.30 No. 1 p.5 ~ p.9
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Clinical Factors Associated with Recurrence of Nasopharyngeal Carcinoma
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Ok So-Hea
Lee Soo-Hyung
Hwang Sun-Jin
Park Min-Woo
Cho Jae-Gu
Baek Seung-Kuk
Kwon Soon-Young
Jung Kwang-Yoon
Woo Jeong-Soo
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Abstract
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Background and Objectives : The objective of this study was to investigate clinical factors associated with recurrence of nasopharyngeal carcinoma(NPC). Materials and Methods : We performed a retrospective review of 112 diagnosed as nasopharyngeal carcinoma, treated concurrent chemo-radiotherapy(CCRT) and had complete response from March 1, 1995, to March 31, 2012. Results : Of the recurrent NPC patients, patients received 2nd line chemotherapy had more recurrence within 2 years(p=0.010). Especially, patients received 2nd line chemotherapy longer than 4 months tend to have recurrence early(p=0.035). Other factors are not different between recurrent and non-recurrent NPC patients. Conclusion : The presence and the duration of 2nd line chemotherapy are associated with early recurrence.
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KEYWORD
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Nasopharyngeal carcinoma, Recurrence, Clinical factor
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